Semaglutide dose chart: Ozempic doses from the label
The Ozempic schedule as the label gives it, with the timing rules around it and a pointer for Wegovy, which uses a different ladder.
The Ozempic label starts semaglutide at 0.25 mg once weekly for 4 weeks, then 0.5 mg once weekly [1]. If more glycemic control is needed after at least 4 weeks, it can go to 1 mg, and after at least 4 weeks on 1 mg, to 2 mg, which is the maximum [1]. Wegovy is semaglutide too but has its own schedule up to 2.4 mg, so check the Wegovy page. Your prescriber decides your dose.
Before you read the chart
Ozempic dose schedule
| Step | Dose, once weekly | What the label says |
|---|---|---|
| Initiation | 0.25 mg for 4 weeks | Initiate at 0.25 mg once weekly for 4 weeks to reduce the risk of gastrointestinal side effects [1] |
| After 4 weeks | 0.5 mg | Increase to 0.5 mg once weekly [1] |
| If more control is needed, after at least 4 weeks on 0.5 mg | 1 mg | The dose may be increased to 1 mg [1] |
| If more control is needed, after at least 4 weeks on 1 mg | 2 mg | The dose may be increased to 2 mg, the maximum [1] |
The recommended maintenance dose is 0.5 mg, 1 mg or 2 mg once weekly, based on glycemic control [1]. For people with type 2 diabetes and chronic kidney disease, the label says to increase to the 1 mg maintenance dose after at least 4 weeks on 0.5 mg [1].
Pens and syringes
Ozempic comes as single-patient-use pens that hold several weekly doses, and as single-dose prefilled syringes in 0.25, 0.5 and 1 mg [1]. The pen strengths on the label are 2 mg per 3 mL (for 0.25 or 0.5 mg doses), 4 mg per 3 mL (1 mg) and 8 mg per 3 mL (2 mg) [1]. Which pen you have depends on your prescribed dose.
Keep a log of your own
Timing rules
Wegovy is different
Wegovy (also semaglutide) starts at 0.25 mg like Ozempic but steps every 4 weeks through 0.5, 1 and 1.7 mg to a maintenance dose of 2.4 mg, and there is also a 7.2 mg strength and a daily tablet [2]. Do not mix the two schedules up. See the Wegovy dosing schedule.
Frequently asked questions
What is the starting dose of Ozempic?
0.25 mg injected once weekly for 4 weeks, then 0.5 mg once weekly, according to the label.
What is the maximum Ozempic dose?
2 mg once weekly.
How long should I stay on each Ozempic dose?
After the 4-week start, the label says an increase can be considered after at least 4 weeks on the current dose, if more glycemic control is needed. Your prescriber decides.
Is the Ozempic dose the same as Wegovy?
No. Both are semaglutide but they have different schedules and strengths. Wegovy’s maintenance dose is 2.4 mg, with a 7.2 mg option for some adults.
Can I change my Ozempic day?
Yes, as long as the time between two doses is at least 2 days (more than 48 hours).
Sources
- OZEMPIC (semaglutide) injection: full prescribing information. Novo Nordisk, revised 05/2026. Sections 2.1 and 2.2 (administration, missed dose, dosage) and 3 (strengths).
- WEGOVY (semaglutide) injection and tablets: full prescribing information. Novo Nordisk, revised 06/2026. Sections 2.1 to 2.5 (administration, dosage, missed doses, switching) and 3 (strengths).
How we write these. Every dose, interval and window above comes from the manufacturer’s US prescribing information, checked on 6 October 2026, and links to it. Labels are updated, so check the current label or ask your pharmacist before you act. Nerra is made by Hicham Zaidi. We do not sell any medicine and are not affiliated with any manufacturer. If you spot an error, tell us through the Nerra support page.
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